We believe that knowledge and policy-making based on strong evidence and critical thinking can improve the quality of people’s lives.

  • interested in evidence-based recommendations – we offer a lot of fresh resources!
  • conducting systematic reviews – read about the tools and automation that can make your work more efficient
  • developing guidelines – join our global community and share your experiences
  • who is a policy maker – increase your knowledge and gain credibility
  • who is a scientist or just loves science – discover how GRADE is essential for your field of science
  • already convinced to GRADE approach – perfect, but just the beginning
  • not convinced to GRADE – it’s time to reconsider the evidence ;)
  • who cares about our planet


The GRADE (Grading of Recommendations Assessment, Development and Evaluation) approach is a system of grading the quality of the underlying evidence, and also a systematic and transparent process for developing recommendations (based on that evidence) for clinical practice, and indicating the strength of those recommendations.

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We call for a "GRADE planet", considering that no reality can be "great" if we deny the achievements of humanity, knowledge, science, logic, kindness, human rights, and universal access to health care. GRADE belongs to a planet-wide community in which science is respected, evidence is desired, doubt is welcome, and where caring for people’s lives, well-being, and health while respecting their values is a mission. There are some moral values that we would like to see become universal values, and the absolute necessity of considering the evidence and evaluating its strength is one of them.

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We feel responsible for our planet and are committed to the health and well-being of all. Therefore, we feel compelled to remind ourselves and others what seems obvious but too often forgotten. That is the reason for the Homo Sapiens Manifesto.
Join our community and help implement knowledge based on evidence in your country, state, village, or just under your roof.